The Fashion Police panellist, who has had more than her share of sartorial slip-ups in her time, this time got it right in a spectacular in a full length plum gown by J Mendel.
Her silvery blonde hair was swept into a French roll, putting her sparkling drop earrings on show.
Elegant: TV personality Kelly Osbourne was among the first to arrive at the 63rd Annual Primetime Emmy Awards held at Nokia Theatre Los Angeles today
And Kelly was clearly thrilled with her look.
After the show, she tweeted: '@J_Mendel i cant thank you enough 4 the amazing dress you lent me 4 tonight's Emmys i don't think i have ever felt this beautiful in my life!'
Glamour: The star enjoyed her moment in the spotlight before beginning her hosting duties for E! News
Red was certainly a popular colour for the evening - despite the risk of blending into the floor - with Rancic, Vampire Diaries star Nina Dobrev in Donna Karen and Glee's Lea Michele in Marchesa all opting for various shades.
Mad Men star Christina Hendricks put her famous car cash curves on show to full effect in a plunge-neck gown by Johanna Johansson.
Go with the flow: Kelly looked confident as she made her way to the ceremony
Jane Lynch of Glee, who is host of the 63rd Primetime Emmys, wore a custom David Meister strapless evening gown in aubergine chiffon with ruched bodice.
Top Chef host Padma Lakshmi, in Armani Privé and So You Think You Can Dance presenter Cat Deeley both flew the flag for Britain in stylish gold dresses.